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Efficiency of centrifugation of chylose samples for selected parameters

Publication at Faculty of Medicine in Pilsen |
2022

Abstract

Aim of the study: the aim of the study is to quantitatively describe the interference of Chylosity with a set of routinely measured methods (27 selected methods) and to determine the efficiency of centrifugation bias.

Methods.

Results: 198 pairs of samples (before and after centrifugation) with varying chylosity were analyzed (minimum; median and maximum of arbitrary units before -> after centrifugation: 33 -> 1; 213 -> 32; 2113 -> 273; 95% CI for decrease = -192 to -161, p < 0.0001). Centrifugation allowed results to be issued according to the manufacturer's specification in the vast majority of cases.

Conclusion: Centrifugation is an effective method of sample preparation that leads to analytically accurate results in most cases, even for chylosic samples.