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Common problems in pharmacotherapy related to kidney diseases - focused on psychotropic medication

Publication at First Faculty of Medicine |
2022

Abstract

Chronic renal insufficiency affects approximately 10% of the domestic population, and the risk of the disease rises sharply with increasing age. Kidney disease and the need for dialysis can have a significant impact on psychological well-being, with depression and anxiety disorders significantly affecting quality of life.

If psychopharmacotherapy is indicated due to the severity of psychiatric symptomatology, dose adjustment is necessary when prescribing agents that are predominantly renally excreted. On the other hand, the adverse side effects of individual psychotropic substances on renal function should be known in order to avoid renal damage.

Finally, knowledge of the risks of pharmacological interactions is essential for safe and tolerable pharmacotherapy when combining psychotropic drugs with drugs for the treatment of renal disease.