Publication at Faculty of Medicine in Hradec Králové |
2022
Abstract
Despite significant scientific efforts, a causal treatment for amyotrophic lateral sclerosis still does not exist. Advances in genetic testing and the discovery of new genes associated with the disease also lead to the idea that the cause of the disease is not the same in all patients, but may be multiple.
Different lifestyle factors can act on different genetic predispositions, resulting in neuron damage in different ways. Perhaps this is why targeted and really effective treatment is not available for patients.
However, there are promising neuroprotective preparations that could at least slow down the progression of the disease. The first gene therapy for a small subset of patients is on the horizon.