Publication at Faculty of Medicine in Hradec Králové |
2022
Abstract
Prolactinomas are the most common hormonally active pituitary adenomas. For women, amenorrhea or other menstrual disturbances are common symptoms of the disease.
Diagnosis is based on the detection of hyperprolactinaemia with verification of the adenoma in the region of the Turkish saddle using magnetic resonance imaging. In most cases, cabergoline alone has a good effect.
The treatment of macroprolactinomas must be individually considered; a combination of several modalities, such as surgery or gamma-knife irradiation followed by drug therapy, is applied.