Palladium catalysis is a versatile strategy for the synthesis of many different kinds of compounds, including formation of heterocycles. Thanks to the possibility to combine more reactions catalysed by palladium complexes into a one-pot transformation, molecular complexity can be substantially increased in only one chemical step, which makes these transformations very efficient.
In this chapter, the use of one particular combination of Pd-catalysed reactions, alkyne carbopalladation and Suzuki cross-coupling for the synthesis of heterocyclic compounds is reviewed.