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Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy

Publication at Central Library of Charles University |
2021

Abstract

The evidence supporting surgical aneurysmectomy in ischemic heart failure is inconsistent. The aim of the study was to describe long-term effect of minimally invasive hybrid transcatheter and minithoracotomy left ventricular (LV) reconstruction in patients with ischemic cardiomyopathy.

Twenty-three subjects with transmural anterior wall scarring, LV ejection fraction 15-45%, and New York Heart Association class >= II were intervened using Revivent TC anchoring system. LV end-systolic volume index was reduced from 73.2 +/- 27 ml at baseline to 51.5 +/- 22 ml after 6 months (p < 0.001), 49.9 +/- 20 ml after 2 years (p < 0.001), and 56.1 +/- 16 ml after 5 years (p = 0.047).

NYHA class improved significantly at 5 years compared to baseline. Six-min walk test distance increased at 2 years compared to the 6-month visit.

Hybrid LV reconstruction using the anchoring system provides significant and durable LV volume reduction during 5-year follow-up in preselected patients with ischemic heart failure.