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Age-related macular degeneration - new treatment options

Publication at Faculty of Medicine in Hradec Králové |
2023

Abstract

Age-related macular degeneration (AMD) is the most common cause of vision loss in people over the age of 65 in developed countries. In most patients, a dry form of AMD is noted, which gradually progresses.

Choroidal neovascular membrane is the main sign of wet form of AMD which is present in 10 % of patients approximately. AMD develops because of an interaction between genetic and lifestyle factors of patients.

The treatment of the choice of the wet form of AMD is intravitreal anti-vascular endothelial growth factor injections, in the case of the dry form of AMD we can choose dietary supplements with lutein and haemorheopheresis. Treatment of the dry form of AMD with intravitreal administration of complement inhibitors is currently under investigation.

An essential prerequisite for successful treatment is early diagnosis and especially early initiation of the treatment.