SARS-CoV-2 predisposes patients to thrombotic disease due to excessive inflammation, platelet activation, endothelial dysfunction, and stasis. The infection was recognized as an independent risk factor for acute myocardial infarction (AMI), which is considered part of the clinical picture of the COVID-19 disease.
Cardiovascular disease increases both the susceptibility to SARS-COV-2 and the risk of death in patients with COVID-19. Among those who died and were COVID PCR-positive, almost one-third (30%) suffered from ischemic heart disease.