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Prognostic factors in metastatic prostate cancer

Publication at First Faculty of Medicine |
2023

Abstract

Metastatic prostate cancer (mPC) is a heterogeneous group of diseases with a median survival of 42 months. The basic treatment of mPC is always a combined treatment with androgen deprivation therapy (ADT - androgen deprivation therapy) with new antiandrogens (ARTA - androgen receptor targeted agents) such as enzalutamide, apalutamide, darolutamide or with the new testosterone synthesis blocker abiraterone acetate (AA) or with chemotherapy (docetaxel, cabazitaxel).

To determine prognosis, we use prognostic factors that correlate with survival independent of systemic therapy. In this article, we provide an overview of the currently used prognostic factors.