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Types and characteristics of renal lesions - diagnosis, treatment and prognosis

Publication at Faculty of Medicine in Hradec Králové |
2023

Abstract

Characteristics of renal lesions may predict further development of the disease, its prognosis and thus becomes part of the decision-making process, as to which treatment strategy to choose, right from the beginning. Unfortunately, a simple TMN classification of the disease stage may not always be sufficient.

Some of the centrally localized renal cell carcinomas (RCC) may be re-evaluated from the primary stage cT1 to the final pathological stage pT3a. Cystic renal lesions represent another specific group in the evaluation of RCC.

Their diagnostic work up and treatment strategy is guided by the Bosniak classification based on the CT. The clinical approach towards the cysts of IIF and III categories may be difficult at least in some cases.

According to the available data up to 3-10% of the Bosniak category IIF complex renal cysts may be malignant, while up to 49% of the category III cysts may be benign. In general, the prognosis of cystic tumors is better than that of the solid tumors