Charles Explorer logo
🇬🇧

Surgical treatment of resectable and borderline resectable pancreatic cancer

Publication at Third Faculty of Medicine |
2023

Abstract

Surgical treatment remains the only treatment method that gives patients hope of cure, or of a significant prolongation of the asymptomatic period. In combination with multimodal oncological treatment, survival of patients has improved in recent years, although from the point of view of other cancers of the gastrointestinal tract it continues to be one of the worst.

The mortality rate of patients operated in large centers ranges between 3-5%, although the morbidity due to the complexity of the procedure and the predominantly higher age composition of patients remains around 40%. A single examination is sufficient for the indication and the right decision on treatment, which is a well-performed CT scan with a pancreatic protocol.

Due to the rate of growth, the timely initiation of treatment is decisive for the fate of patients. The stratification of patients indicated for therapy according to their initial CT findings has changed significantly.

Patients with localized disease are indicated for surgical therapy primarily, others only after undergoing neoadjuvant therapy.