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Case reports of patients with ALK-positive NSCLC and brain metastases

Publication at First Faculty of Medicine |
2023

Abstract

The present case reports describe a young male and a young female patient diagnosed with generalized non-small cell lung adeno­carcinoma with brain metastases and ALK translocation. Brain metastases are detected in 30% of patients with ALK-positive NSCLC at the time of cancer diagnosis.

The discussion section deals with the intracranial efficacy of individual ALK inhibitors.