Breast-conserving surgical treatment combined with perioperative systemic therapy and postoperative radiotherapy is the standard treatment for early-stage breast carcinoma. Mastectomy continues to be performed in patients in whom breast-conserving surgery cannot be recommended for therapeutic or cosmetic reasons.
They often have locally or regionally advanced disease in which mastectomy is virtually always followed by adjuvant radiotherapy. Breast reconstruction following mastectomy is increasingly encountered, and this trend will continue to grow in the future.
With advances in medicine, there has been progress in both the surgical procedures used in reconstruction and the technical aspects of radiotherapy. The issue of correct combination and timing of reconstruction and adjuvant radiotherapy continues to raise numerous questions which the present review article attempts to address.