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Pharmacomechanical thrombectomy is an effective and safe method of treating deep vein thrombosis. We present preliminary follow-up results in our patient cohort

Publication at Faculty of Medicine in Hradec Králové |
2023

Abstract

Purpose: Early thrombus removal techniques have been introduced to improve the effectiveness of deep vein thrombosis (DVT) treatment. This paper evaluates results of pharmacomechanical thrombectomy (PMT) in patients with acute iliofemoral (IF) DVT.

Methods: 20 patients (8 males and 12 females, age range 16-75 years) with acute IF DVT underwent PMT using the Angiojet device, in 70% in combination with catheter-directed thrombolysis (CDT). The patency of the recanalized venous segment was verified ultrasonographically before discharge and subsequently at 3, 6, 12-month follow-up and annually thereafter.

Obtained data were analyzed retrospectively. Results: Recanalization was achieved in all patients, in 20% at primary PMT, in 80% after subsequent CDT and repeated interventions.

A venous stent was inserted in 40%. The median total amount of administered thrombolytic was 34 mg.

The median duration of endovascular treatment was 21 hours, and the median total hospital stay was 6 days. A clinically relevant non-major bleeding complication occurred in 3 patients (15%).

During follow-up 1 year after the procedure, 100% patency of the recanalized venous segment was maintained. Conclusion: In our study, we demonstrated high efficacy and safety of IF DVT treatment with PMT.

The patency of the recanalized venous segment was preserved in all cases 1 year after the procedure.