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Drug-induced liver injury (DILI)

Publication at First Faculty of Medicine |
2023

Abstract

The most common hepatotoxic drugs in children are antibiotics and antiepileptics. DILI is presents mostly with 2 patterns of injury: hepatocellular or cholestatic.

Diagnosis can be done with help of the Roussel Uclaf Causality Assessment Method (RUCAM). The mainstay of treatment is prompt withdrawal of the suspect drug.