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Hyperlipidemic crisis as a risk factor for acute pancreatitis

Publication at Faculty of Medicine in Hradec Králové |
2023

Abstract

Hypertriglyceridemia is one of the conditions that can cause one of the most severe forms of acute pancreatitis (AP). There is a very high risk of developing persistent multi-organ failure and abdominal catastrophe [1].

The incidence of acute pancreatitis due to hypertriglyceridemia is increasing worldwide. Given the inappropriate dietary habits of mainly Western populations, the obesity pandemic and lack of exercise, this trend can be expected to intensify [2].

The aforementioned causes currently account for up to one-third of AP cases in some populations. Acute pancreatitis typically develops when hypertriglyceridemia is > 1,000 mg/dl (> 11.3 mmol/l).

Although the specific treatment of acute pancreatitis is still unknown, there is a possibility of using an intervention in the form of therapeutic plasmapheresis, with which we have long experience at our department.