Abstract
Aging is associated with neurodegeneration and a loss of muscle function, especially in lower-limb muscles. While caffeine may augment muscle force generation through multiple effects on the central nervous system, no studies have yet compared the effects of caffeine on force-generating capacity between younger and older men, who might respond differently due to age-related changes in the structures on which caffeine acts.
In a double-blind, controlled trial, 22 younger (25 +/- 5 years) and 21 older (68 +/- 6 years) men were tested for isometric plantarflexor torque on two separate days (2-7 days apart) before and 60 min after ingesting 3 mg/kg (similar to 2 cups of coffee) of caffeine or placebo. No effects of caffeine ingestion on peak torque or rate of torque development were detected in either older or younger men.
Therefore, 3 mg/kg of caffeine may not acutely counteract age-related decreases in force capacity of the functionally important plantarflexor muscles.