Photochemical Access to Substituted β-Lactams and β-Lactones via the Zimmerman-O'Connell-Griffin Rearrangement
2023
Abstrakt
A photomediated protocol giving facile access to substituted β-lactam and β-lactones is presented. The method realizes, for the first time, the use of the Zimmerman-O'Connell-Griffin (ZOG) rearrangement in [2 + 2] cycloaddition.
Products are obtained in high yield with excellent diastereoselectivity under visible light irradiation and under mild reaction conditions.