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A three-day fasting test as an aid for deciding on treatment de-escalation in long-term diabetics

Publication at Faculty of Medicine in Pilsen |
2023

Abstract

The aim of the article is to show that with the help of a three-day fasting test, it is possible to simplify the treatment and make it more efficient even in diabetics generally considered to be "hopeless". Two case reports show patients with long-standing type 2 diabetes mellitus and with chronic decompensation despite the treatment with high-dose intensive insulin regimen (IIR).

Using the fasting test, we verified sufficient residual insulin secretion, and by switching to a fixed combination of GLP-1 analogue and basal insulin, we improved not only their compensation but also other parameters and especially the quality of life.