Publication at Second Faculty of Medicine, Faculty of Medicine in Hradec Králové |
2023
Abstract
Idiopathic steroid-sensitive nephrotic syndrome is the most common pediatric glomerulopathy. Most of the patients have favorable outcome, however 50% of children suffer from frequently relapsing course or they are steroid dependent.
At present, several steroid sparing agents are available, which are administered to induce sustained remission and to prevent steroid side effects. Here, we review current knowledge in diagnostics and management of steroid-sensitive nephrotic syndrome in children.