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Effect of immunotherapy and radiotherapy in the treatment of Merkel cell carcinoma in a patient with myelodysplastic syndrome

Publication at First Faculty of Medicine |
2023

Abstract

The authors present a case of a complete treatment response in a patient treated for metastatic Merkel cell carcinoma with a combination of radiotherapy and immunotherapy with avelumab. Immunotherapy was terminated prematurely due to relapse of myelodysplastic syndrome.

Despite premature termination of immunotherapy, complete disease remission has been sustained. Clinical and histopathological properties of Merkel cell carcinoma and the recommended treatment algorithm are discussed.

Attention is paid to the management of avelumab treatment.