A failure of Fourier transform infrared spectroscopy to type Burkholderia isolates from chronically infected patients with cystic fibrosis

Abstract

We noted high variability of isolates spectra that prevented assigning isolates to known ST. Moreover, the FT-IR failed to reliably determine whether a chronic patient harbored the same Burkholderia strain over the course of infection.

As such, we conclude that the method is not suitable for Burkholderia strain typing.

Keywords

• Fourier transform infrared spectroscopy
• Burkholderia cenocepacia
• cystic fibrosis