Abstract
Azulene hydrazido-hydrazones of general formula I have a 2-hydroxyaryl group, where R1, R2, R3, R4 are independent H, OH, alkyl with 1 to 6 carbon atoms, C(CH3)3, allyl, benzyl, phenyl, F, Cl, Br, I, CH2OH, O(alkyl), CF3, OCF3, CN, COO(alkyl), CONH(alkyl), NO2, N(alkyl)2, NH(alkyl), NHCO(alkyl), where the alkyl has 1 to 6 carbon atoms, or R1-R2 or R2-R3 or R3-R4 is -CH=CH-CH=CH-, i.e. a condensed benzene nucleus. These compounds show a selective cytostatic effect and can be used for the preparation of drugs for the treatment of oncological diseases.