In the last two decades research has been focused on the development of biologically-derived matrices for reconstructive medicine[1]. Decellularized tissues from a xenogeneic donor represent a growth-friendly environment for cells of different species, including human, lacking most of the immunogenic components[2].
Decellularized porcine liver resembles the human counterpart and could be considered for reconstruction of human liver tissue in vitro. Thus there is a high need for bioreactor development where the effective cell repopulation can be achieved using a good quality scaffold.