Non-traumatic compartment syndrome is a serious condition that affects muscle compartments typically in patients after ischemic insult during acute limb ischemia and can have serious consequences for the affected limb and the patient's overall health. This syndrome is characterized by increased pressure in the intrafascial space, leading to compression of muscles, blood vessels and nerves leading to worsening ischemia and even irreversible damage to these structures.
Early diagnosis and treatment are crucial to reduce the risk of complications and preserve limb function. In this article, we review the definition, pathophysiology and important clinical aspects of non-traumatic compartment syndrome.