Osimertinib belongs to the tyrosine kinase inhibitors of the 3rd generation, highly effective also in the area of the central nervous system. The treatment is reserved for patients with a positive mutation of the epidermal growth factor receptor (EGFR) in non-small cell lung cancer.
It is currently reimbursed for patients with advanced or generalized disease, however, it also proved effective in the adjuvant phase, as evidenced by our case report.