Abstract
The circulatory system plays one of the key roles in the concept of oxygen delivery to tissues. In a simplified concept and for the needs of clinical reasoning, the circulatory system consists of two basic components - macrocirculation (so-called large and small circulation) and microcirculation.
Both components are functionally connected to each other by a number of regulatory mechanisms, the correct function of macrocirculation and microcirculation is the basis of the so-called hemodynamic coherence. The article describes the basic components of the macrocirculation as a starting point for a structured balance and understanding of the effect/interrelationship of therapeutic interventions in the most common conditions that manifest themselves as "circulatory disorders" in clinical practice.
