VICTORY project: impact of complex pharmacotherapy on compensation of patients with type 2 diabetes mellitus
Abstract
Type 2 diabetes (T2D) is a major medical problem, as it is a disease of increasing prevalence with a range of microvascular and macrovascular complications that require costly treatment. The VICTORY project was designed as a non-interventional prospective multicenter trial to investigate the efficacy and safety of intensive complex therapy in patients with expressed insulin resistance (IR) or T2D in real clinical practice.
The main aim of this project was to characterize the cohort in detail, to identify possible explanations for the lack of control in the patients studied and, last but not least, to analyze the impact of the initial intervention over a time horizon of 6-12 months. The results of the VICTORY project are an important mirror of common clinical practice, which shows unsatisfactory control of both T2D and associated comorbidities.
However, the positi-ve message remains that if intervention is thought of, even in a relatively short timeframe (6-12 months) - through comprehensive patient management - better compensation can be achieved. The choice of appropriate antidiabetic, antihypertensive or lipid-lowering treatment, hand in hand with regimen measures and diet modification, can have a profound effect on morbidity and mortality in diabetics.