Abstract
Transthyretin amyloidosis of the heart (ATTR) is a progressive disease caused by the deposition of insoluble transthyretin in the myocardium. Finally it can lead to heart failure.
It occurs predominantly in men over the age of 70. This disease should be considered in differential diagnosis by elderly patients with heart failure, cardiac arrhythmias or conduction disorders (especially atrioventricular conduction disorders) and left ventricular wall thickening of unclear etiology.
In case of suspected ATTR, the patient should be early sent for specialized cardiological examination, which includes echocardiography, myocardial scintigraphy, magnetic resonance imaging or myocardial biopsy. With early diagnosis, except for symptomatic treatment, there is also specific therapy available.
In this case we present 76years-old polymorbid patient, repeatedly hospitalized for heart failure, who was diagnosed with transthyretin amyloidosis of the heart and we discusse current treatment options for this disease.