Abstrakt
Renal changes can have long-term consequences, and their prevention is the main goal of vesicoureteral reflux (VUR) treatment. Renal scintigraphy using 99mTc-DMSA scan is considered as the gold standard to prove the presence and extent of renal parenchymal changes and to determine split renal function.
The position of the 99mTc-DMSA scan in initial VUR diagnosis is a matter of debate. Both bottom-up and top-down approaches have their strong and weak points. Regardless of which approach is chosen, the goal must be to establish diagnosis of VUR as early as possible and to determine the status of renal parenchyma [1,2].
Renal scarring is the most significant predictor of breakthrough febrile UTI in patients with VUR and is a negative prognostic factor for spontaneous reflux resolution [3,4].
The aim of this study was to determine the risk of renal damage in children diagnosed with VUR grade III, which is generally considered (along with VUR I and II) as a low-grade VUR, according to the occurrence of renal changes using the 99mTc-DMSA scan grading.