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Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice

Publication at Faculty of Science, Faculty of Mathematics and Physics |
2008

Abstract

We investigated the soluble forms of the earliest activation antigen of human leukocyte CD69. We describe the physical, biochemical and in vivo characteristics of a highly stable soluble form of CD69 obtained by bacterial expression of an appropriate extracellular segment of this protein.