Pharmacokinetics of azathioprine during the first weeks of treatment of Crohn´s disease and ulcerative colitis in children and adolescents

Abstract

Description of pharmacokinetics and time until steady-state of 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine nucleotides (6-MMPN) following initiation of azathioprine (AZA) treatment in paediatric inflammatory bowel disease (IBD).

Keywords

• Inflammatory bowel disease
• azathioprine
• pharmacokinetics
• children