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The Stem Cell Marker CD133 (Prominin-1) Is Expressed in Various Human Glandular Epithelia

Publication at Faculty of Medicine in Hradec Králové |
2008

Abstract

Human prominin-1 (CD133) is defined by the widely used mAb AC133 it is expressed by various stem cells originating from diverse sources. In this study, we reinvestigated its expression profile using a novel mAb80B258 generated against the prominin-1 polypeptide.

Remarkably our data reveal that its overall expression is beyond the rare primitive cells, and it seems to be a general marker of the apical membrane of glandular epithelia.