Publication at First Faculty of Medicine |
2008
Abstract
The aim of this surveillance study was to assess the tolerability of, and response to 6.month treatment with escitalopram in 525 psychiatric out-patient clinics in the Czech Republic. Clinical response was evaluated using the Zung Depression Rating Scale and the Clinical Impressions--Improvement scale.
The patients showed an improvement in their severity of depression, with a response rate of 86.7% and a remission rate of 80.6% for patients completing 6 months of treatment. The most frequent adverse events were nausea, headache and sweating. 3.7% of patients withdrew from the study because of non-response and/or worsening of psychopathology.