Publication at First Faculty of Medicine |
2004
Abstract
Even though coffee is not considered to be responsible for development of peptic ulcer, it may, however, prolong its healing by increasing acidity of gastric content. In our former work we observed a profound increase in sucrose permeability (above normal values) in healthy volunteers regularly drinking coffee for years.
In literature, many factors affecting sucrose permeability have been described so far. None of them, however, studied the effect of coffee.
Our results indicate that coffee may damage gastroduodenal mucosa in habitual coffee drinkers. In a time period of 48hours the gastroduodenal mucosa is capable of a significant regeneration.