Publication at First Faculty of Medicine |
2006
Abstract
Idiopathic hypereosinophilic syndrome is a heterogenous group of hematological disorders characterized by eosinopholia (>1,5*109/1) persistent for more than 6 month, exclusion of reactive eosinophilia from other causes, such as parasitic infections or allergy, and evidence of end-organ damage. Other therapeutical options for HES/CEL have been mentioned.
The resistence to imatinib and the possibilities how to overcome in treatment of HES it are discussed.