Publication at First Faculty of Medicine |
2007
Abstract
The multisystem involvement in cystic fibrosis (CF) patients may alter body composition and influence bone metabolism, leading to low bone minerál densi-ty and lean body mass depletion. Peripheral quantitative computed tomography (pQCT) allows assessment of volumetric bone minerál density and assessment of the relationship between bones and muscles.
The thinner cortical bone found in CF patients may be due to their lower muscle mass. Changes in bone minerál density in CF háve to be evaluated with caution.