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The vegetable sterols in diabetics

Publication at First Faculty of Medicine |
2004

Abstract

Plant sterols occur naturally in plants and vegetable oils. Sitosterol and campesterol are markers of cholesterol absorption.

The ratio of cholesterol endogenous synthesis to its absorption may be assessed by sitosterol, campesterol and other non-cholesterol sterols (lathosterol and squalen) serum concentration measurements. In 38 Type 2 diabetics and in 40 non-diabetics plant sterols serum concentration were measured: lathosterol, squalen, sitosterol and campesterol.

In non-diabetics squalen positive correlates with C-peptid, lathosterol with triacylglycerols and campesterol with HbA1c. In diabetics correlates diabetes compensation with plant sterols value negative.

It seems that plant sterols and probably also cholesterol absorption can be influenced negative by higher value HbA1c.