Severe lactic acidosis associated with acute renal failure in a diabetic patient treated with metformin - A case study

Abstract

Here we have outlined a case in which lactic acidosis developed during treatment of a diabetic patient in whom there were no contraindications to metformin treatment. Lactic acidosis was caused by acute renal failure leading to metformin accumulation.

The acute renal failure was caused by a combination of dehydration due to a low intake of fluids when disabled decause of a fractured ankle, concomitant diuretic treatment of arterial hypetension and angiotensin - convertin enzyme inhibitor treatment.

Keywords

• Severe
• lactic
• acidosis
• associated
• acute
• renal
• failure
• diabetic
• patient
• treated
• metformin
• study