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Lithium microdialysis and its use for monitoring of stomach and colon submucosal blood perfusion - a pilot study using ischemic preconditioning in rats

Publication at First Faculty of Medicine |
2006

Abstract

Ischemic preconditioning elevates nitric oxide and blood perfusion, whereby it protects organs against subsequent severe ischemia/reperfusion. Using a flow marker, microdialysis serves to monitor interstitial microcirculation.

This study tested the reliability of lithium as a flow marker on a model of ischemic preconditioning and found that lithium microdialysis appears to be a potentially suitable indicator of gastrointestinal interstitial microcirculation.