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Prognostic significance of ischemia modified albumin after percutaneous coronary intervention

Publication at First Faculty of Medicine |
2006

Abstract

Ischemia modified albumin (IMA) is a new biochemical marker of ischemia. IMA levels rise in patients who develop ischemia during percutaneous coronary intervention (PCI).

It is unclear whether IMA elevations correlate with PCI variables. The possible prognostic value of post-PCI IMA elevation has not yet to be studied.

We 60 patients who underwent successful elective single-vessel PCI for the management of stable angina pectoris. IMA levels were measured and comared with PCI variables and target lesion revascularization rate.

The median post-PCI follow up is 46 months. We found that the only variable related to post-PCI IMA levels was periprocedural dissection of target vessel.

No correlation between high and low balloon inflation pressure, short and long inflation 130 kU/l was associated with higher freqeuncy of target lesion revascularization at nearly 4-yeart follow-up. Post-PCI IMA elevation is associated with higher target lesion ravascularization.