MDOC and atorvastatin gave potential antiinflammatory effects in vascular endothelium of apoE mouse model of atherosclerosis

Abstract

These results provide new information of potential hypolipidem cubstance MDOC and its potential anti-inflammatory effects. Furthermore, we have confirmed anti-inflammatory effects of atorvastatin independent of plasma cholesterol lowering.

Thus, the results of this study show potential bnefit of both MDOC and atorvastatin treatment in apoE mouse model of atherosclerosis suggesting their possible combination might be of interest.

Keywords

• Cell adhesion molecules
• MDOC
• Atorvastatin
• Simvastatin
• atherosclerosis
• mice