Stem cells from human exfoliated deciduous teeth - isolation, long term cultivation and phenotypical analysis
2010
Abstract
Aims: Our aims were to isolate stem cells from human exfoliated deciduous teeth (SHED), to cultivate them in vitro and to investigate their basic biological properties, phenotype and to compare our findings with dental pulp stem cells (DPSC) isolated from permanent teeth. Conclusions: We isolated stem cells from exfoliated teeth.
In comparison to DPSC, SHED proliferation rate was about 50 % slower, and SHED showed slightly different phenotype.These cells may be extremely useful for stem cell tissue banking, further stem cell research and future therapeutic applications.