- Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA2008 | Faculty of Science
- Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine2007 | Faculty of Science, Second Faculty of Medicine, Central Library of Charles University
- An efficient modification of ellipticine synthesis and preparation of 13-hydroxyellipticine2007 | Faculty of Science, First Faculty of Medicine, Faculty of Mathematics and Physics
- The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide2004 | Faculty of Science
- The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide2004 | First Faculty of Medicine, Faculty of Mathematics and Physics
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | Faculty of Science, Second Faculty of Medicine
- Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases2012 | Second Faculty of Medicine
- Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine2007 | Second Faculty of Medicine
- Formation and persistence of DNA adducts of anticancer drug ellipticine in rats2007 | Faculty of Science
- The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung2013 | Faculty of Science
- Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy2011 | Faculty of Science
- DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells2007 | Faculty of Science, Second Faculty of Medicine
- Cytochrome P450-and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency2011 | Faculty of Science
- Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b52012 | Faculty of Science
- Cytochrome b(5) plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine2017 | Faculty of Science, Second Faculty of Medicine
- Expression Levels of Enzymes Metabolizing an Anticancer Drug Ellipticine Determined by Electromigration Assays Influence its Cytotoxicity to Cancer Cells - A Comparative Study2014 | Faculty of Science, Second Faculty of Medicine
- Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells2013 | Faculty of Science, Second Faculty of Medicine
- Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells2013 | Publication without faculty affiliation
- Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine2016 | Faculty of Science, Second Faculty of Medicine
- Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine2016 | Faculty of Science