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CYP1A1/2
Publication
Class
Person
Publication
Programmes
publication
CYP1A1/2 and prostaglandin H synthase catalyze reductive activation of inflammatory drug aristolochic acid and that results in DNA adduct formation
2000 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
CYP1A1/2 and prostaglandin H synthase catalyze reductive activation of inflammatory drug aristolochic acid and that results in DNA adduct formation
2000 |
Faculty of Science
publication
The anticancer drug ellipticine acts as an inducer of cytochromes P450 1A1/2 and potentiates its own pharmacological efficiency
2003 |
Faculty of Science
publication
Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy
2011 |
Faculty of Science
publication
Anticancer drug ellipticine forms DNA adducts in vivo; A novel mode of its antineoplatic action
2004 |
Faculty of Science
publication
Identification of microsomal enzymes activating carcinogenic aristolochic acid in human
2003 |
Faculty of Science
publication
Identification of microsomal enzymes activating carcinogenic aristolochic acid in human
2003 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
ANTICANCER DRUG ELLIPTICINE ACTS AS AN INDUCER OF CYTOCHROMES P450 1A1/2 AND POTENTIATES ITS OWN PHARMACOLOGICAL EFFICIENCY
2003 |
Faculty of Science
publication
ANTICANCER DRUG ELLIPTICINE ACTS AS AN INDUCER OF CYTOCHROMES P450 1A1/2 AND POTENTIATES ITS OWN PHARMACOLOGICAL EFFICIENCY
2003 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
The anticancer drug ellipticine acts as an inducer of cytochromes P450 1A1/2 and potentiates its own pharmacological efficiency
2003 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes
2009 |
Central Library of Charles University
publication
Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes
2009 |
Faculty of Pharmacy in Hradec Králové
publication
Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Role of dihydromyricetin in cytochrome P450-mediated metabolism and carcinogen activation
2015 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens
2011 |
Faculty of Science
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Second Faculty of Medicine
publication
Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
2016 |
Faculty of Science
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Faculty of Science
publication
The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice
2013 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung
2013 |
Faculty of Science
publication
Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats
2011 |
Faculty of Science
publication
The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat
2013 |
Faculty of Science
publication
Impact of smoking on metabolic changes and effectiveness of drugs used for lung cancer
2020 |
First Faculty of Medicine
publication
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches
2014 |
Faculty of Science
publication
Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1
2012