- Isopropenylmethyl-derivatives of adamantane and diamantane are selective inhibitors of CYP2B4 and CYP2B6.2000 | Faculty of Science
- Isopropenylmethyl-derivatives of adamantane and diamantane are selective inhibitors of CYP2B4 and CYP2B6.2000 | First Faculty of Medicine, Faculty of Mathematics and Physics
- Memantine: new selective in vitro inhibitor of CYP2B6Publication without faculty affiliation
- Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: Secondary analysis of the Euro-Ewing99-R1 trial2015 | Second Faculty of Medicine
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Faculty of Pharmacy in Hradec Králové
- Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling2018 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance2019 | Faculty of Pharmacy in Hradec Králové
- In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity2022 | Faculty of Pharmacy in Hradec Králové
- Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
- The Role of Cytochromes P450 and Aldo-Keto Reductases in Prognosis of Breast Carcinoma Patients2014 | First Faculty of Medicine, Second Faculty of Medicine
- Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities2017 | Faculty of Science
- Effect of genetic variation in CYP450 on Gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach: Results from the pancareLIFE study2021 | Second Faculty of Medicine
- Deeper Insight into the Reducing Biotransformation of Bupropion in the Human LiverPublication without faculty affiliation
- Deeper Insight into the Reducing Biotransformation of Bupropion in the Human Liver2014 | Faculty of Pharmacy in Hradec Králové
- Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor2017 | Faculty of Pharmacy in Hradec Králové
- Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation2017 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)2015 | Faculty of Pharmacy in Hradec Králové
- Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro2016 | Faculty of Pharmacy in Hradec Králové
- Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction2018 | Faculty of Science, Faculty of Pharmacy in Hradec Králové
- Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids2022 | Faculty of Pharmacy in Hradec Králové
- Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes2019 | Faculty of Pharmacy in Hradec Králové
- Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme2020 | Faculty of Pharmacy in Hradec Králové
- Joint analysis of phenotypic and genomic diversity sheds light on the evolution of xenobiotic metabolism in humans2022 | Faculty of Science, Central Library of Charles University, Third Faculty of Medicine
- Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models2018 | Faculty of Pharmacy in Hradec Králové
- Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter2022 | Faculty of Pharmacy in Hradec Králové
- U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells2014 | Faculty of Pharmacy in Hradec Králové