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CYP3A
Publication
Class
Person
Publication
Programmes
publication
Naftoflavone as a model ligand of the active site of CYP3A
2003 |
Faculty of Science
publication
Naftoflavone as a model ligand of the active site of CYP3A
2003 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Influence of CYP3A Metabolizer Status on the Pharmacokinetics and Pharmacodynamics of Amiodarone
2000 |
Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo
2015 |
Faculty of Pharmacy in Hradec Králové
publication
How long does the pharmacokinetic interaction between carbamazepine and quetiapine last after carbamazepine withdrawal?
2017 |
Faculty of Medicine in Pilsen, Third Faculty of Medicine
publication
alfa-naftoflavon jako modelový ligand aktivního centra cytochromu P450 CYP3A4 a CYP3A6
2001 |
Faculty of Science
publication
U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
2007 |
Faculty of Science
publication
The Effect of New Lipophilic Chelators on the Activities of Cytosolic Reductases and P450 Cytochromes Involved in the Metabolism of Anthracycline Antibiotics: Studies in Vitro
2004 |
First Faculty of Medicine
publication
Characterization of enzymes responsible for biotransformation of the new antileukotrienec drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes
2004 |
Faculty of Pharmacy in Hradec Králové
publication
alpha-naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6
2001 |
Faculty of Science
publication
alpha-naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6
2001 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
alfa-naftoflavon jako modelový ligand aktivního centra cytochromu P450 CYP3A4 a CYP3A6
2001 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine
2014 |
Faculty of Pharmacy in Hradec Králové
publication
The inhibitory effects of beta-caryophyllene, beta-caryophyllene oxide and alpha-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Exposure of rats to exogenous endocrine disruptors 17alpha-ethinylestradiol and benzo(a)pyrene and an estrogenic hormone estradiol induces expression of cytochromes P450 involved in their metabolism
2016 |
Faculty of Science
publication
Role of rat cytochromes P450 in the oxidation of 17α-ethinylestradiol
2014 |
Faculty of Science
publication
Predictors of Irinotecan Toxicity and Efficacy in Treatment of Metastatic Colorectal Cancer
2012 |
Faculty of Medicine in Hradec Králové
publication
Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems
2020 |
Faculty of Science, Second Faculty of Medicine
publication
Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction
2018 |
Faculty of Science, Faculty of Pharmacy in Hradec Králové
publication
The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN (TM)) Mice and Pure Enzymes
2015 |
Faculty of Science
publication
Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Second Faculty of Medicine
publication
Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
2019 |
Faculty of Science
publication
Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma
2011 |
Second Faculty of Medicine