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NQO1
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publication
A Dynamic Core in Human NQO1 Controls the Functional and Stability Effects of Ligand Binding and Their Communication across the Enzyme Dimer
2019 |
Faculty of Science, Central Library of Charles University
publication
NQO1*2 polymorphism predicts overall survival in MDS patients
2019 |
First Faculty of Medicine, Faculty of Physical Education and Sport
publication
An Association of the NQO1 C609T Inactivating Polymorphism with Pediatric Burkitt's Lymphoma
2001 |
Second Faculty of Medicine
publication
Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations
2022 |
Faculty of Science, Central Library of Charles University
publication
Breast cancer: role of polymorphisms in biotransformation enzymes
2004 |
Second Faculty of Medicine
publication
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation
2022 |
Faculty of Science, Central Library of Charles University
publication
Low Expression of NQO1 Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients treated with TAC Regimen
2012 |
Faculty of Medicine in Hradec Králové
publication
Role of gene expression of quinone oxidoreductase 1 and 2 in progression of breast cancer
2007 |
Second Faculty of Medicine
publication
Superoxide Dismutase and Nicotinamide Adenine Dinucleotide Phosphate Quinone Oxidoreductase Polymorphisms and Pancreatic Cancer Risk
2011 |
First Faculty of Medicine
publication
NAD(P)H:quinone oxidoreductase 1 Pro187Ser polymorphism and expression do not cosegregate with clinico-pathological characteristcs of human mammary tumors
2009 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Role of gene expression of quinone oxidoreductase 1 and 2 in progression of breast cancer
2007 |
First Faculty of Medicine
publication
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
2021 |
Faculty of Science, Central Library of Charles University
publication
The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells
2009 |
Central Library of Charles University
publication
The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats-A comparative study
2014 |
Faculty of Science
publication
Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo
2014 |
Faculty of Science
publication
NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I
2012 |
Faculty of Science
publication
Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase
2003 |
Faculty of Science
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Second Faculty of Medicine
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Superoxide Dismutase and Nicotinamide Adenine Dinucleotide Phosphate Quinone Oxidoreductase Polymorphisms and Pancreatic Cancer Risk
2011 |
Second Faculty of Medicine
publication
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases
2011 |
Faculty of Science
publication
Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats
2011 |
Faculty of Science
publication
Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice
2015 |
Faculty of Pharmacy in Hradec Králové
publication
The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats
2014 |
Faculty of Science
publication
Toxic Effects of the Major Components of Diesel Exhaust in Human Alveolar Basal Epithelial Cells (A549)
2016 |
Faculty of Science
publication
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer
2013 |
Faculty of Science
publication
The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats
2015 |
Faculty of Science