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human carcinogen
Publication
Class
Person
Publication
Programmes
publication
Metabolic activation of the suspected human carcinogen 3-nitrobenzanthrone by human hepatic microsomes and recombinant cytochromes P450
2003 |
First Faculty of Medicine, Faculty of Mathematics and Physics
publication
The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen
2005 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogen o-anisidine
2005 |
Faculty of Science
publication
Metabolic activation of the suspected human carcinogen 3-nitrobenzanthrone by human hepatic microsomes and recombinant cytochromes P450
2003 |
Faculty of Science
publication
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
2014 |
Faculty of Science
publication
Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes
2008 |
Faculty of Science, Central Library of Charles University
publication
Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers
2005 |
Faculty of Science
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Second Faculty of Medicine
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b(5)
2014 |
Faculty of Science, Second Faculty of Medicine
publication
Mutagenic Potential of Nitrenium Ions of Nitrobenzanthrones: Correlation Between Theory and Experiment
2008 |
Faculty of Science
publication
Chances and limitations of use of epidemiological data at the risk assessment of carcinogenity
2012 |
First Faculty of Medicine
publication
In-Home Coal and Wood Use and Lung Cancer Risk: A Pooled Analysis of the International Lung Cancer Consortium
2010 |
First Faculty of Medicine
publication
The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and-1A2 and NAD(P) H : quinone oxidoreductase
2006 |
Faculty of Science
publication
Toxicity of the mycotoxin ochratoxin A in the light of recent data
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Faculty of Science
publication
A simple identification of novel carbonyl reducing enzymes in the metabolism of the tobacco specific carcinogen NNK
2012 |
Faculty of Pharmacy in Hradec Králové
publication
The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat
2013 |
Faculty of Science
publication
The History, Toxicity and Adverse Human Health and Environmental Effects Related to the Use of Agent Orange
2013 |
First Faculty of Medicine
publication
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
2017 |
Faculty of Science
publication
Can proteomics predict the prognosis in chronic dioxin intoxication?
2019 |
Faculty of Science, First Faculty of Medicine
publication
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
2016 |
Faculty of Science
publication
The Role of Cytochrome P450 Enzymes in Carcinogen Metabolism: Lessons Learned From Studies With Benzo[a]pyrene and Aristolochic Acid
2018 |
Faculty of Science
publication
Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes
2012 |
Faculty of Science
publication
Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine
2016 |
Faculty of Science
publication
NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
2016 |
Faculty of Science
publication
Exposure of rats to exogenous endocrine disruptors 17alpha-ethinylestradiol and benzo(a)pyrene and an estrogenic hormone estradiol induces expression of cytochromes P450 involved in their metabolism
2016 |
Faculty of Science
publication
Markers of lipid oxidative damage in the exhaled breath condensate of nano TiO2 production workers
2017 |
First Faculty of Medicine, Faculty of Physical Education and Sport, Central Library of Charles University
publication
NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
2016 |
Faculty of Science