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nitroreduction
Publication
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publication
Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1
2016 |
Faculty of Science
publication
Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1
2012 |
Faculty of Science
publication
A role of biotransformation enzymes in the Development of renal injury and urothelial cancer caused by aristolochic acid: Urgent questions difficult answers
2009 |
Faculty of Science
publication
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway
2024 |
Faculty of Pharmacy in Hradec Králové
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Second Faculty of Medicine
publication
The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Role of P450 1A1 and P450 1A2 in Bioactivation versus Detoxication of the Renal Carcinogen Aristolochic Acid I: Studies in Cyp1a1(-/-), Cyp1a2(-/-), and Cyp1a1/1a2(-/-) Mice
2011 |
Faculty of Science
publication
Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2
2012 |
Faculty of Science